Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7314734 | 0.92 | AR (0.38) | PLA2G2AALOX5APPPARGSLC2A1PTGES2 | |
| Trifluoroacetic Acid SCHEMBL7315970 | 0.91 | CCR2 (0.41) | PLA2G2AALOX5APGRIN1GRIN2BSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL7318205 | 0.88 | ICMT (0.41) | PLA2G2AGRIN1GRIN2BPPARG | |
| Trifluoroacetic Acid SCHEMBL7316949 | 0.83 | ABCB11 (0.40) | PLA2G2AGRIN1GRIN2BPTGES2ADAM17 | |
| Trifluoroacetic Acid SCHEMBL7585777 | 0.83 | EGFR (0.46) | PLA2G2AALOX5APPPARG | |
| Trifluoroacetic Acid SCHEMBL7403856 | 0.71 | PTGDR2 (0.40) | MDM2PTGDR2RXRARXRGSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL7315177 | 0.68 | EGFR (0.54) | PLA2G2APPARG | |
| Trifluoroacetic Acid SCHEMBL7320899 | 0.66 | SERPINE1 (0.33) | PTGDR2PPARGSERPINE1 | |
| Trifluoroacetic Acid SCHEMBL3750230 | 0.66 | FFAR1 (0.49) | SLC2A1 | |
| Trifluoroacetic Acid SCHEMBL27502598 | 0.64 | FFAR1 (0.52) | PTGDR2RXRARXRGPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | MDM2 4182/4885PLA2G2A 2102/4885ALOX5AP 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.