Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.70 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | NQO2 | P16083 | 2/20 | 0.52 |
| ▸ | SPR | P35270 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319151 | 0.88 | IDO1 (0.58) | MTNR1AMTNR1BMEN1KMT2ATRPV1 | |
| SCHEMBL8613795 | 0.87 | TRPV1 (0.55) | MTNR1AMTNR1BMEN1KMT2ATRPV1 | |
| SCHEMBL31077788 | 0.87 | TRPV1 (0.70) | MEN1KMT2ATRPV1CYP1A2NOTUM | |
| SCHEMBL798165 | 0.87 | TRPV1 (0.70) | MEN1KMT2ATRPV1CYP1A2NOTUM | |
| SCHEMBL2544150 | 0.86 | HPGD (0.55) | MTNR1AMTNR1BMEN1KMT2ATRPV1 | |
| SCHEMBL8194888 | 0.86 | NOTUM (0.70) | MTNR1AMTNR1BTRPV1NOTUMSPR | |
| SCHEMBL6927448 | 0.85 | MTNR1A (0.74) | MTNR1AMTNR1BMEN1KMT2ATRPV1 | |
| SCHEMBL8807970 | 0.85 | HTR7 (0.57) | MTNR1AMTNR1BMEN1KMT2ATRPV1 | |
| SCHEMBL8806792 | 0.85 | TRPV1 (0.53) | MTNR1AMTNR1BMEN1KMT2ATRPV1 | |
| Trimethylammonium SCHEMBL8321230 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BMEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |
| US-5726177-A | HEADACHES; ANXIOLYTIC AGENTS, ANTIDEPRESSANTS, ANALGESICS | PIERRE FABRE MEDICAMENT (FR) | 1998-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | MTNR1A 4451/4885MTNR1B 4294/4885MEN1 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.