Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 4/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
| ▸ | SDC2 | P34741 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330386 | 0.95 | PSMB1 (0.42) | SYKCASP1CTSDRENKLK5 | |
| Hydrochloric Acid SCHEMBL7331042 | 0.84 | CASP1 (0.43) | CASP1CTSDCTSBCTSKIL1RN | |
| SCHEMBL7319638 | 0.84 | CTSK (0.46) | CASP1CTSDRENCTSBCTSK | |
| SCHEMBL7323095 | 0.81 | ERAP2 (0.43) | CASP1CTSDCTSBCTSKIL1RN | |
| SCHEMBL7332099 | 0.81 | LNPEP (0.37) | CASP1CTSDCTSBCTSKIL1RN | |
| SCHEMBL7326123 | 0.81 | SYK (0.48) | SYKCTSDRENKLK5CTSB | |
| Hydrochloric Acid SCHEMBL7323783 | 0.81 | ERAP2 (0.42) | CASP1CTSDCTSBCTSKIL1RN | |
| SCHEMBL7329312 | 0.80 | CTSD (0.42) | CASP1CTSDMEN1KMT2A | |
| SCHEMBL7321477 | 0.79 | CASP1 (0.46) | CASP1CTSDMEN1KMT2A | |
| SCHEMBL10376907 | 0.79 | LTA4H (0.43) | IL1RNERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |