Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 4/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323405 | 0.95 | SYK (0.46) | SYKCASP1CTSKRENCTSD | |
| SCHEMBL10376907 | 0.86 | LTA4H (0.43) | LTA4H | |
| Hydrochloric Acid SCHEMBL7324002 | 0.85 | LTA4H (0.42) | LTA4H | |
| SCHEMBL7323172 | 0.83 | SYK (0.43) | PSMB1PSMB5PSMB2SYKPSMB8 | |
| SCHEMBL7324428 | 0.81 | LTA4H (0.44) | PSMB1PSMB5PSMB2SYKLTA4H | |
| Hydrochloric Acid SCHEMBL7331042 | 0.79 | CASP1 (0.43) | CASP1CTSKCTSD | |
| SCHEMBL7319638 | 0.79 | CTSK (0.46) | CASP1CTSKRENCTSD | |
| SCHEMBL7323095 | 0.79 | ERAP2 (0.43) | CASP1CTSKCTSD | |
| Hydrochloric Acid SCHEMBL7323783 | 0.78 | ERAP2 (0.42) | CASP1CTSKCTSD | |
| SCHEMBL7332099 | 0.77 | LNPEP (0.37) | CASP1CTSKCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |