Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88110 | 0.80 | LMNA (0.50) | ALDH1A1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL29740308 | 0.80 | LMNA (0.50) | ALDH1A1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL1490778 | 0.79 | NUDT1 (0.42) | ALDH1A1KMT2AKDM4EMAPTDHFR | |
| SCHEMBL29740307 | 0.79 | LMNA (0.48) | ALDH1A1KMT2AKDM4EMAPTNUDT1 | |
| SCHEMBL2815837 | 0.77 | ADRA2A (0.35) | ALDH1A1KMT2AKDM4EMAPTDHFR | |
| SCHEMBL22733525 | 0.77 | ADRA2A (0.41) | ALDH1A1KMT2AKDM4EMAPTDHFR | |
| SCHEMBL15893398 | 0.77 | HTR3E (0.42) | ALDH1A1KMT2AKDM4EMAPTDHFR | |
| SCHEMBL5942607 | 0.73 | TGFBR1 (0.39) | ALDH1A1KMT2AKDM4EMAPTGAA | |
| SCHEMBL21712334 | 0.72 | DYRK1A (0.37) | ALDH1A1KMT2AKDM4EMAPTDHFR | |
| SCHEMBL30107098 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTBLMNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535104-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1996-09-04 | — | — | EP | disclosed |
| US-5276028-A | Psychological disorders, anticonvulsants, anxiolytic or hypnotics and cognition activators | NORDISK A/S (DK) | 1994-01-04 | — | — | US | disclosed |
| EP-0535104-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1993-04-07 | — | — | EP | disclosed |
| WO-1992000298-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-09 | — | — | WO | disclosed |