Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7328932 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1KMT2AFKBP1ANPC1 | |
| SCHEMBL7328952 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL16370933 | 0.67 | L3MBTL1 (0.71) | KDM4EALDH1A1KMT2ALMNASMN1; SMN2 | |
| Oxalic Acid SCHEMBL7328944 | 0.66 | KDM4E (0.50) | KDM4EALDH1A1KMT2ALMNATHRB | |
| SCHEMBL7328956 | 0.64 | ALDH1A1 (0.56) | KDM4EALDH1A1KMT2ANPC1LMNA | |
| SCHEMBL16370936 | 0.63 | ALDH1A1 (0.46) | KDM4EALDH1A1KMT2AFKBP1ANPC1 | |
| SCHEMBL28001062 | 0.63 | LMNA (0.53) | KDM4EALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL27983752 | 0.63 | ALDH1A1 (0.50) | ALDH1A1KMT2ATHRBSMN1; SMN2POLB | |
| SCHEMBL3822896 | 0.62 | L3MBTL1 (0.41) | KDM4EALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL16463810 | 0.62 | TSHR (0.43) | KDM4EALDH1A1KMT2AFKBP1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629190-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | disclosed |
| WO-1993015052-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | disclosed |