Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7328932 | 0.93 | KDM4E (0.48) | KDM4EALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL7328937 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL16370933 | 0.72 | L3MBTL1 (0.71) | KDM4EALDH1A1KMT2ASIGMAR1L3MBTL1 | |
| SCHEMBL24352743 | 0.72 | FKBP1A (0.57) | ALDH1A1NPC1KMT2AMEN1SIGMAR1 | |
| SCHEMBL7328956 | 0.71 | ALDH1A1 (0.56) | KDM4EALDH1A1NPC1KMT2ASIGMAR1 | |
| SCHEMBL16370936 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL25299662 | 0.69 | TSHR (0.57) | KDM4EALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL8682004 | 0.67 | PNMT (0.50) | KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL28001062 | 0.67 | LMNA (0.53) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8682006 | 0.67 | PNMT (0.50) | KDM4EALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629190-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-12-21 | — | — | EP | claimed |
| WO-1993015052-A1 | COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-08-05 | — | — | WO | claimed |