Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337649 | 0.88 | KMT2A (0.43) | CTSSKMT2A | |
| SCHEMBL7339105 | 0.88 | HSD17B10 (0.37) | CTSSKMT2A | |
| SCHEMBL7339877 | 0.87 | LMNA (0.38) | CTSSKMT2A | |
| SCHEMBL7339560 | 0.85 | REN (0.36) | CTSS | |
| SCHEMBL7338555 | 0.85 | REN (0.36) | CTSSKMT2A | |
| SCHEMBL7331624 | 0.85 | FFAR2 (0.32) | CTSS | |
| SCHEMBL7339274 | 0.85 | TSHR (0.34) | — | |
| SCHEMBL7334862 | 0.83 | RORC (0.33) | CTSSKMT2A | |
| SCHEMBL7333699 | 0.82 | REN (0.38) | CTSSKMT2A | |
| SCHEMBL7328094 | 0.82 | CTSS (0.32) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332742-A | Ocular hypotensive | ABBOTT LABORATORIES (US) | 1994-07-26 | — | — | US | disclosed |
| US-5310740-A | Congestive heart failure, hypotensive agents, antiglaucoma agents; side effect reduction | ABBOTT LABORATORIES (US) | 1994-05-10 | — | — | US | disclosed |
| US-5284849-A | Treating hypertension and congestive heart failure | ABBOTT LABORATORIES (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0456185-A2 | Renin inhibitors | ABBOTT LABORATORIES (US) | 1991-11-13 | — | — | EP | disclosed |