Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698186 | 0.83 | ALDH1A1 (0.47) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7372058 | 0.76 | ALDH1A1 (0.38) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL8725706 | 0.75 | POLB (0.45) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL7352882 | 0.74 | POLB (0.36) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL18983310 | 0.74 | HTT (0.41) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL4762963 | 0.73 | POLB (0.52) | LMNAMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5318428 | 0.72 | LIPG (0.45) | LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL28515355 | 0.71 | MTNR1A (0.52) | LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL31265560 | 0.71 | SLC6A4 (0.57) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL8016874 | 0.71 | SLC6A4 (0.57) | MEN1KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892885-A | CARDIOTONICS, DIURETICS | AMERICAN CYANAMID COMPANY | 1990-01-09 | — | — | US | disclosed |