Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343029 | 0.76 | LMNA (0.43) | ALDH1A1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15698186 | 0.73 | ALDH1A1 (0.47) | ALDH1A1POLBHTTMAPTMEN1 | |
| SCHEMBL11037286 | 0.72 | SLC6A2 (0.54) | ALDH1A1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4583268 | 0.70 | TSHR (0.44) | ALDH1A1POLBHTTMAPTALOX15 | |
| SCHEMBL28222416 | 0.69 | ADRB2 (0.53) | ALDH1A1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8725706 | 0.69 | POLB (0.45) | ALDH1A1KDM4EPOLBHTTMAPT | |
| SCHEMBL7170913 | 0.69 | NPC1 (0.37) | ALDH1A1KDM4EPOLBHTTMAPT | |
| SCHEMBL14292004 | 0.68 | MPO (0.49) | ALDH1A1SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8018072 | 0.68 | TSHR (0.67) | KDM4ESLC6A4TSHRPKM | |
| SCHEMBL1083028 | 0.68 | SLC6A2 (0.47) | ALDH1A1KDM4ESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892885-A | CARDIOTONICS, DIURETICS | AMERICAN CYANAMID COMPANY | 1990-01-09 | — | — | US | disclosed |