Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15698186 | 0.79 | ALDH1A1 (0.47) | POLBALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7343029 | 0.75 | LMNA (0.43) | POLBALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL18983310 | 0.74 | HTT (0.41) | POLBALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL4762963 | 0.73 | POLB (0.52) | POLBALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7372058 | 0.69 | ALDH1A1 (0.38) | POLBALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL5318428 | 0.69 | LIPG (0.45) | KMT2AMEN1NPSR1LMNA | |
| SCHEMBL29539230 | 0.69 | CYP3A4 (0.56) | POLBALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL12317648 | 0.69 | CYP3A4 (0.56) | POLBALDH1A1HTTKMT2AMEN1 | |
| Triphenylphosphine Oxide SCHEMBL8431247 | 0.68 | CA2 (0.63) | POLBALDH1A1HTTKMT2AMEN1 | |
| Triphenylphosphine Oxide SCHEMBL8431251 | 0.68 | CA2 (0.63) | POLBALDH1A1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830915-A | ORAL DISEASES; SKIN DISORDERS; ANTIINFLAMMATORY AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-11-03 | — | — | US | disclosed |