Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | BMP1 | P13497 | 1/20 | 0.49 |
| ▸ | BRS3 | P32247 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7354156 | 0.86 | KMT2A (0.55) | NMBRMEN1KMT2ABRS3MAPT | |
| SCHEMBL7341910 | 0.84 | MEN1 (0.42) | NMBRMEN1KMT2AMAPT | |
| SCHEMBL7433554 | 0.84 | CTSL (0.40) | MAPT | |
| SCHEMBL7384083 | 0.82 | NMBR (0.43) | NMBRMEN1KMT2ACA2BMP1 | |
| SCHEMBL7434571 | 0.79 | ADAM17 (0.37) | MAPT | |
| SCHEMBL7433267 | 0.79 | CTSL (0.54) | NMBR | |
| SCHEMBL10420266 | 0.78 | TACR1 (0.67) | NMBRMEN1KMT2AGAAMAPT | |
| SCHEMBL7348054 | 0.77 | LNPEP (0.63) | NMBR | |
| SCHEMBL7351604 | 0.76 | MMP8 (0.39) | KMT2AHTT | |
| SCHEMBL7434646 | 0.76 | CTSC (0.37) | MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523313-A | HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; INHIBITORS OF NEUTRAL METALLOENDOPEPTIDASES; VASODILATION; HEART FAILURE AND RENAL INSUFFICIENCY | TANABE SEIYAKU CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0690070-A1 | Indole-containing peptide and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |