Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CTSK | P43235 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | NMBR | P28336 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444104 | 0.90 | CTSK (0.46) | CTSLCTSBCTSSCTSKNMBR | |
| SCHEMBL7351604 | 0.86 | MMP8 (0.39) | — | |
| SCHEMBL7433554 | 0.85 | CTSL (0.40) | CTSLCTSBCTSSCTSK | |
| SCHEMBL9113871 | 0.82 | CTSL (0.73) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL13073498 | 0.81 | CTSL (0.71) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7764124 | 0.81 | CTSL (0.71) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7434571 | 0.80 | ADAM17 (0.37) | — | |
| SCHEMBL7443335 | 0.80 | MAPT (0.53) | TGM2 | |
| SCHEMBL17643540 | 0.80 | CTSL (0.76) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL7429208 | 0.79 | L3MBTL1 (0.52) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |