Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MPI | P34949 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353482 | 0.86 | DRD2 (0.44) | DRD2ACKR3DGAT1KMT2AALDH1A1 | |
| SCHEMBL7348412 | 0.85 | SMN1; SMN2 (0.48) | ACKR3DGAT1KMT2AALDH1A1LMNA | |
| SCHEMBL7348115 | 0.85 | DRD2 (0.47) | DRD2ACKR3ALDH1A1CYP1A2HTR1A | |
| SCHEMBL7353206 | 0.84 | DRD2 (0.46) | DRD2ACKR3HTR2ANR1I2CYP1A2 | |
| SCHEMBL7348549 | 0.79 | ALDH1A1 (0.44) | DRD2ACKR3DGAT1KMT2AALDH1A1 | |
| SCHEMBL7353056 | 0.79 | DRD2 (0.46) | DRD2ACKR3HTR1ADRD3 | |
| SCHEMBL7357845 | 0.74 | ALDH1A1 (0.57) | ACKR3DGAT1KMT2AALDH1A1LMNA | |
| SCHEMBL11900526 | 0.73 | DGAT1 (0.56) | ACKR3DGAT1KMT2AALDH1A1LMNA | |
| SCHEMBL7354269 | 0.73 | DRD2 (0.63) | DRD2KMT2ATSHRHTR2ANR1I2 | |
| SCHEMBL7350207 | 0.72 | SIGMAR1 (0.34) | DRD2LMNAHTR2ANR1I2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |