Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350499 | 0.88 | DRD2 (0.44) | DRD2ACKR3HTR1ADRD3 | |
| SCHEMBL7344193 | 0.87 | ALDH1A1 (0.47) | DRD2ACKR3HTR1A | |
| SCHEMBL7353206 | 0.85 | DRD2 (0.46) | DRD2ACKR3HTR7HTR1ADRD4 | |
| SCHEMBL7348115 | 0.84 | DRD2 (0.47) | DRD2ACKR3HTR7HTR1ADRD4 | |
| SCHEMBL7354269 | 0.80 | DRD2 (0.63) | DRD2HTR7HTR1ADRD4DRD3 | |
| SCHEMBL7344636 | 0.79 | DRD2 (0.47) | DRD2ACKR3HTR1ADRD3 | |
| SCHEMBL7354659 | 0.79 | HTR1A (0.38) | DRD2ACKR3HTR7HTR1ADRD3 | |
| SCHEMBL10745051 | 0.76 | DRD2 (0.81) | DRD2HTR7HTR1ADRD4DRD3 | |
| SCHEMBL7353631 | 0.75 | MAPT (0.38) | DRD2ACKR3 | |
| SCHEMBL10692044 | 0.73 | DRD2 (0.73) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | claimed |
| EP-0972764-A1 | Aminoalcohols and aminoketones as CNS active agents | Universita Degli Studi di Firenze (IT) | 2000-01-19 | — | — | EP | disclosed |