Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.42 |
| ▸ | MMP9 | P14780 | 9/20 | 0.42 |
| ▸ | MMP1 | P03956 | 7/20 | 0.42 |
| ▸ | MMP13 | P45452 | 6/20 | 0.42 |
| ▸ | MMP3 | P08254 | 6/20 | 0.42 |
| ▸ | MMP14 | P50281 | 4/20 | 0.34 |
| ▸ | MMP8 | P22894 | 3/20 | 0.34 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7344740 | 0.78 | CTSS (0.47) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL7337160 | 0.70 | CTSK (0.47) | RENMAPTHTT | |
| SCHEMBL5350533 | 0.61 | CTSS (0.52) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL5350528 | 0.61 | CTSS (0.52) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL5277957 | 0.61 | CTSS (0.52) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL14932686 | 0.61 | CTSS (0.52) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL7054085 | 0.60 | MMP2 (1.00) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL7333112 | 0.59 | CTSS (0.48) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL7333126 | 0.59 | CTSS (0.48) | MMP2MMP9MMP1MMP13MMP3 | |
| SCHEMBL7053943 | 0.59 | MMP2 (0.80) | MMP2MMP9MMP1MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416117-A | Protease inhibitor | MITSUBISHI KASEI CORPORATION (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0520427-B1 | Cyclopropenone derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5328909-A | Protease inhibitors | MITSUBISHI KASEI CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0520427-A1 | Cyclopropenone derivatives | Mitsubishi Chemical Corporation (JP) | 1992-12-30 | — | — | EP | disclosed |