Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351859 | 0.90 | ALDH1A1 (0.38) | ALDH1A1TSHRGAASMN1; SMN2RORC | |
| SCHEMBL7344143 | 0.81 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2LMNATHRATHRB | |
| SCHEMBL7346510 | 0.78 | KMT2A (0.37) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL7350727 | 0.77 | NR3C1 (0.46) | ALDH1A1TSHRGAARORCMAPT | |
| SCHEMBL7346501 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRCA12CA1CA2 | |
| SCHEMBL7348710 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRCA1CA2RORC | |
| SCHEMBL7343576 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TSHRSMN1; SMN2RORCLMNA | |
| SCHEMBL7351856 | 0.72 | RORC (0.38) | ALDH1A1TSHRCA1CA2SMN1; SMN2 | |
| SCHEMBL2688609 | 0.72 | LMNA (0.48) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL7351863 | 0.70 | KMT2A (0.41) | ALDH1A1TSHRRORCKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284971-A | No cardiac side effects | SYNTEX (U.S.A.) INC. (US) | 1994-02-08 | — | — | US | disclosed |