Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351604 | 0.80 | MMP8 (0.39) | KMT2A | |
| SCHEMBL7433267 | 0.76 | CTSL (0.54) | — | |
| SCHEMBL7432459 | 0.74 | CHRNB2 (0.38) | MAPTCA1ALDH1A1MEN1KMT2A | |
| SCHEMBL7443335 | 0.74 | MAPT (0.53) | MAPTLMNAALDH1A1RAB9A | |
| SCHEMBL7433554 | 0.74 | CTSL (0.40) | MAPTPOLB | |
| SCHEMBL7429208 | 0.73 | L3MBTL1 (0.52) | MAPTCA2CA1LMNA | |
| SCHEMBL7434588 | 0.73 | PPARG (0.36) | MAPTCA1KMT2APOLB | |
| SCHEMBL9599593 | 0.72 | TACR2 (0.38) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL504326 | 0.71 | KMT2A (0.51) | MAPTCA2CA1LMNAMEN1 | |
| SCHEMBL12203721 | 0.71 | L3MBTL1 (0.49) | MAPTLMNAALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523313-A | HYPOTENSIVE AGENTS; CARDIOTONIC AGENTS; INHIBITORS OF NEUTRAL METALLOENDOPEPTIDASES; VASODILATION; HEART FAILURE AND RENAL INSUFFICIENCY | TANABE SEIYAKU CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0690070-A1 | Indole-containing peptide and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |