Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322208 | 0.78 | CA2 (0.33) | NPSR1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL362355 | 0.76 | CA2 (0.44) | NPSR1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7331788 | 0.75 | CA2 (0.33) | NPSR1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL7331335 | 0.74 | KMT2A (0.48) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL7346734 | 0.72 | MAPT (0.39) | GAAALDH1A1TSHR | |
| SCHEMBL7334090 | 0.71 | ALDH1A1 (0.38) | NPSR1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL8902905 | 0.71 | NPSR1 (0.49) | NPSR1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7352882 | 0.71 | POLB (0.36) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL28194592 | 0.70 | USP2 (0.61) | NPSR1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL7350255 | 0.70 | TSHR (0.39) | GAAMEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3995486-A1 | PEPTIDE AND METHOD FOR MANUFACTURING SAME | AGC INC. (JP) | 2022-05-11 | — | — | EP | disclosed |
| US-20220119440-A1 | PEPTIDE AND METHOD FOR MANUFACTURING SAME | AGC Inc. (JP) | 2022-04-21 | — | — | US | disclosed |
| US-9365522-B2 | Pyrazole amide derivative | AMGEN INC. (US) | 2016-06-14 | — | — | US | disclosed |
| US-20150266824-A1 | Pyrazole Amide Derivative | TEIJIN LIMITED (JP) | 2015-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266824-A1 | Pyrazole Amide Derivative | RORC, RORB, RORA | NPSR1 2299/4885GAA 3413/4885MEN1 4091/4885 |
| US-20220119440-A1 | PEPTIDE AND METHOD FOR MANUFACTURING SAME | VIP, RFC2, QRFPR | NPSR1 1728/4885GAA 4287/4885MEN1 947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.