Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.42 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | POLG | P54098 | 2/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 4/20 | 0.38 |
| ▸ | DUT | P33316 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21317432 | 1.00 | POLB (0.46) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL11986900 | 1.00 | POLB (0.46) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL4580611 | 0.92 | POLB (0.46) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL26233616 | 0.90 | POLB (0.46) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL9548879 | 0.89 | LMNA (0.50) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL9548876 | 0.89 | LMNA (0.50) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL4580042 | 0.88 | POLB (0.44) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL4580039 | 0.88 | POLB (0.44) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL21563935 | 0.88 | TOP2A (0.42) | POLBP2RY2P2RY4TOP2ADUT | |
| SCHEMBL21778225 | 0.87 | POLB (0.43) | POLBLMNAPDE3ACACNA1FALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4704831-A2 | SUBSTITUTED PYRIMIDINONE AND AZAPYRIMIDINONE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024226983-A2 | SUBSTITUTED PYRIMIDINONE AND AZAPYRIMIDINONE COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2024-10-31 | — | — | WO | disclosed |
| EP-4404942-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2024-07-31 | — | — | EP | disclosed |
| EP-4240849-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | Wave Life Sciences Ltd. (SG) | 2023-09-13 | — | — | EP | disclosed |
| US-20230264164-A1 | HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY | TRILINK BIOTECHNOLOGIES, LLC | 2023-08-24 | — | — | US | disclosed |
| WO-2023049477-A2 | COMPOSITIONS FOR EDITING MECP2 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| US-11612873-B2 | Homopolymer encoded nucleic acid memory | Molecular Assemblies, Inc. (US) | 2023-03-28 | — | — | US | disclosed |
| WO-2020219853-A1 | HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY | Molecular Assemblies, Inc. (US) | 2020-10-29 | — | — | WO | disclosed |
| US-20190344239-A1 | HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY | Molecular Assemblies, Inc. | 2019-11-14 | — | — | US | disclosed |
| US-10444220-B2 | Controlled tunnel gap device for sequencing polymers | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2019-10-15 | — | — | US | disclosed |
| US-9140682-B2 | Controlled tunnel gap device for sequencing polymers | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-09-22 | — | — | US | disclosed |
| US-8969535-B2 | Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130072388-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2013-03-21 | — | — | US | disclosed |
| US-8361727-B2 | 3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20120288948-A1 | CONTROLLED TUNNEL GAP DEVICE FOR SEQUENCING POLYMERS | ARIZONA BOARD OF REGENTS (US) | 2012-11-15 | — | — | US | disclosed |
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |
| US-7897737-B2 | Polymorphic identification; fluorescent dyes | LASERGEN, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090081686-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN DNA SEQUENCING | AGILENT TECHNOLOGIES, INC. | 2009-03-26 | — | — | US | disclosed |
| US-20080132692-A1 | Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing | AGILENT TECHNOLOGIES, INC. | 2008-06-05 | — | — | US | disclosed |
| US-20080064867-A1 | PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | SIGMA ALDRICH COMPANY (US) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132692-A1 | Photocleavable labeled nucleotides and nucleosides and methods for their use in DNA sequencing | UNG, DCLRE1B, NT5C3B | POLB 28/4885LMNA 131/4885PDE3A 1553/4885 |
| US-20080064867-A1 | PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | RNGTT, DUT, ADAR | POLB 26/4885LMNA 1388/4885PDE3A 2280/4885 |
| US-20130072388-A1 | PHOTOCLEAVABLE LABELED NUCLEOTIDES AND NUCLEOSIDES AND METHODS FOR THEIR USE IN IN DNA SEQUENCING | UNG, NT5C3B, OGG1 | POLB 29/4885LMNA 129/4885PDE3A 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.