SCHEMBL735093

SCHEMBL735093

NP(O)OC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.67
SLC28A2 O43868 1/20 0.67
SLC29A1 Q99808 1/20 0.67
SLC28A3 Q9HAS3 1/20 0.67
P2RY6 Q15077 8/20 0.65
P2RY2 P41231 11/20 0.64
P2RY4 P51582 5/20 0.64
P2RY14 Q15391 6/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912731 0.91 P2RY6 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL23344550 0.90 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL28889687 0.90 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL31229960 0.90 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL336760 0.89 SLC28A1 (0.69) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL21678787 0.88 P2RY6 (0.66) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL25174534 0.88 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL4741075 0.86 SLC28A1 (0.72) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL4950157 0.86 SLC28A1 (0.72) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL21742397 0.86 SLC28A1 (0.65) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076620-A Process for producing 2' -modified pyrimidine nucleoside 日产化学株式会社 2024-05-24 CN claimed
CN-115181147-B Preparation method of C4 '-trifluoromethylthio modified nucleoside and C4' -trifluoromethylthio modified nucleic acid 南开大学 2024-04-02 CN claimed
CN-109071588-A Uridine phosphamide prodrug, preparation method and application thereof in medicine 江苏天士力帝益药业有限公司 2018-12-21 CN claimed
US-9920319-B2 2′/3′/5′-(R/S)-serinyl functionalized oligonucleotides COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2018-03-20 US claimed
US-20170044527-A1 Novel 2'/3'/5'-(R/S)-Serinyl Functionalized Oligonucleotides COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-02-16 US claimed
WO-2014178082-A1 NOVEL 2'/3'/5'-(R/S)-SERINYL FUNCTIONALIZED OLIGONUCLEOTIDES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-11-06 WO claimed
CN-104011209-A Inhibition Of Viral Gene Expression UNIV WITWATERSRAND JHB 2014-08-27 CN claimed
US-20120178710-A1 SYNTHESIS OF CYCLIC DIGUANOSINE MONOPHOSPHATE AND THIOPHOSPHATE ANALOGS THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-07-12 US claimed
EP-2448954-A1 SYNTHESIS OF CYCLIC DIGUANOSINE MONOPHOSPHATE AND THIOPHOSPHATE ANALOGS THEREOF Rutgers, The State University of New Jersey (US) 2012-05-09 EP claimed
WO-2011003025-A1 SYNTHESIS OF CYCLIC DIGUANOSINE MONOPHOSPHATE AND THIOPHOSPHATE ANALOGS THEREOF RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-01-06 WO claimed
WO-2008080060-A2 4-SE-THYMIDINE DERIVATIVES, 4-SE-URIDINE DERIVATIVES, DI (2-CYANOETHYL) DISELENIDE, AND METHODS GEORGIA STATE UNIVERSITY (US) 2008-07-03 WO claimed
US-12629426-B2 Muscle targeting complexes and uses thereof for treating dystrophinopathies DYNE THERAPEUTICS, INC. (US) 2026-05-19 US disclosed
US-12624120-B2 Anti-transferrin receptor (TfR) antibody and uses thereof DYNE THERAPEUTICS, INC. (US) 2026-05-12 US disclosed
US-20260109989-A1 COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND IDENTIFICATION OF COVALENT APTAMERS UNIV HAWAII (US) 2026-04-23 US disclosed
EP-4694931-A1 EXTRAHEPATIC DELIVERY OF DOUBLE-STRANDED RNA AGENTS Alnylam Pharmaceuticals, Inc. (US) 2026-02-18 EP disclosed
WO-1995006659-A1 AMINE-DERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES ISIS PHARMACEUTICALS, INC. (US) 1995-03-09 WO disclosed
EP-0635023-A1 COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. (US) 1995-01-25 EP disclosed
WO-1994002501-A1 NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF ISIS PHARMACEUTICALS, INC. (US) 1994-02-03 WO disclosed
EP-0571087-A1 Cleavable phosphoramidites ROHM AND HAAS COMPANY (US) 1993-11-24 EP disclosed
WO-1993018052-A1 COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. (US) 1993-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624120-B2 Anti-transferrin receptor (TfR) antibody and uses thereof FTH1, TFRC, VSIG8 SLC28A1 2554/4885SLC28A2 2540/4885SLC29A1 1224/4885
US-20260109989-A1 COMPOSITIONS AND METHODS FOR THE SYNTHESIS AND IDENTIFICATION OF COVALENT APTAMERS DNMT3A, PCNA, DNMT3L SLC28A1 329/4885SLC28A2 446/4885SLC29A1 29/4885
US-20170044527-A1 Novel 2'/3'/5'-(R/S)-Serinyl Functionalized Oligonucleotides RNGTT, NSUN2, ADAR SLC28A1 1046/4885SLC28A2 657/4885SLC29A1 448/4885
US-20120178710-A1 SYNTHESIS OF CYCLIC DIGUANOSINE MONOPHOSPHATE AND THIOPHOSPHATE ANALOGS THEREOF TYMP, DTYMK, MTAP SLC28A1 359/4885SLC28A2 349/4885SLC29A1 244/4885
US-12629426-B2 Muscle targeting complexes and uses thereof for treating dystrophinopathies MYOF, MUSK, UPF1 SLC28A1 2152/4885SLC28A2 1592/4885SLC29A1 1411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.