Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554369 | 0.90 | GAA (0.46) | PTGESALOX5KDRFLT1FLT4 | |
| SCHEMBL8553174 | 0.90 | PTGES (0.43) | PTGESALOX5KDRFLT1FLT4 | |
| SCHEMBL8553246 | 0.89 | NTRK1 (0.39) | PTGESALOX5KDRFLT1FLT4 | |
| SCHEMBL7355477 | 0.85 | STS (0.40) | PTGESALOX5KDRFLT1FLT4 | |
| SCHEMBL1984012 | 0.85 | NTRK1 (0.48) | PTGESALOX5KDRFLT1FLT4 | |
| SCHEMBL8557168 | 0.84 | GAA (0.44) | PTGESALOX5STSNTRK1ALDH1A1 | |
| SCHEMBL8552075 | 0.83 | FPR1 (0.41) | PTGESALOX5KDRFLT1FLT4 | |
| SCHEMBL8552811 | 0.82 | FPR1 (0.45) | L3MBTL1NTRK1ALDH1A1LMNATSHR | |
| SCHEMBL8556018 | 0.81 | LMNA (0.48) | L3MBTL1NTRK1ALDH1A1LMNAKMT2A | |
| SCHEMBL8555845 | 0.80 | LMNA (0.47) | PTGESALOX5L3MBTL1NTRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |