Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 6/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555343 | 0.92 | FPR1 (0.50) | FPR1L3MBTL1NTRK1SLCO1B1ALDH1A1 | |
| SCHEMBL1984012 | 0.88 | NTRK1 (0.48) | FPR1PTGS1PTGS2FLT1FLT4 | |
| SCHEMBL8554369 | 0.86 | GAA (0.46) | FPR1PTGS1PTGS2FLT1FLT4 | |
| SCHEMBL8552895 | 0.85 | FPR1 (0.48) | FPR1PTGS1PTGS2NTRK1SLCO1B1 | |
| SCHEMBL8553174 | 0.84 | PTGES (0.43) | PTGS1PTGS2FLT1FLT4KDR | |
| SCHEMBL8556673 | 0.83 | PTGES (0.40) | PTGS1PTGS2FLT1FLT4KDR | |
| SCHEMBL8553246 | 0.82 | NTRK1 (0.39) | PTGS1PTGS2FLT1FLT4KDR | |
| SCHEMBL8557168 | 0.81 | GAA (0.44) | FPR1NTRK1PTGESALOX5ALDH1A1 | |
| SCHEMBL8550650 | 0.80 | FPR1 (0.53) | FPR1L3MBTL1NTRK1SLCO1B1ALDH1A1 | |
| SCHEMBL7355477 | 0.79 | STS (0.40) | FLT1FLT4KDRL3MBTL1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |