Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355176 | 0.84 | ICMT (0.44) | ALOX5MAPTKCNH2 | |
| SCHEMBL7357801 | 0.79 | MMP8 (0.45) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL893363 | 0.77 | ALOX5 (0.62) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL7357356 | 0.76 | ALOX5 (0.54) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL1952031 | 0.74 | SIGMAR1 (0.56) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL1955414 | 0.74 | SIGMAR1 (0.56) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL1954766 | 0.74 | SIGMAR1 (0.56) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL16933744 | 0.74 | SIGMAR1 (0.56) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL1954943 | 0.74 | SIGMAR1 (0.56) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL7348490 | 0.74 | ERAP2 (0.43) | ALOX5EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009736-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | Roche Diagnostics GmbH (DE) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011608-A1 | MALONIC ACID BASED MATRIX METALLOPROTEINASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-03-11 | — | — | WO | disclosed |