Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | XBP1 | P17861 | 3/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356630 | 0.85 | CHRNB2 (0.46) | LMNARAB9ANPC1 | |
| SCHEMBL7358428 | 0.84 | EGLN1 (0.40) | SMN1; SMN2LMNARAB9AHTTALDH1A1 | |
| SCHEMBL7355082 | 0.81 | EGLN1 (0.45) | SMN1; SMN2LMNARAB9AHTTALDH1A1 | |
| SCHEMBL7358512 | 0.81 | TRPV4 (0.45) | SMN1; SMN2NOD1MITFLMNARAB9A | |
| SCHEMBL7354930 | 0.79 | NPC1 (0.52) | SMN1; SMN2LMNARAB9AALDH1A1NPSR1 | |
| SCHEMBL7355990 | 0.77 | EGLN3 (0.40) | SMN1; SMN2LMNAHTTALDH1A1KDM4E | |
| SCHEMBL7360967 | 0.76 | TSHR (0.46) | SMN1; SMN2LMNARAB9AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL7357414 | 0.76 | PRPS1 (0.38) | SMN1; SMN2LMNAHTTALDH1A1KMT2A | |
| SCHEMBL7356668 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2LMNARAB9AHTTALDH1A1 | |
| SCHEMBL7353986 | 0.73 | KDM4E (0.36) | SMN1; SMN2LMNAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003298-A1 | BENZIMIDAZOLE DERIVATIVES USEFUL AS DOPAMINE RECEPTOR ANTAGONIST, 5-HT RECEPTOR AGONIST OR α1 RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-02 | — | — | WO | disclosed |