Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280876 | 0.98 | HSD11B1 (0.44) | METAP2HSD11B1HPGDALDH1A1TDP1 | |
| SCHEMBL30877175 | 0.92 | FAAH (0.42) | METAP2HPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7641554 | 0.88 | CYP1A2 (0.46) | METAP2FAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25062701 | 0.84 | METAP2 (0.41) | METAP2HSD11B1HPGDALDH1A1TDP1 | |
| SCHEMBL16761652 | 0.82 | NAAA (0.36) | METAP2ALDH1A1TDP1L3MBTL1FAAH | |
| SCHEMBL2648207 | 0.81 | MEN1 (0.51) | HPGDALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL4590410 | 0.81 | ALDH1A1 (0.39) | METAP2HPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL23458431 | 0.80 | METAP2 (0.34) | METAP2HSD11B1HPGDALDH1A1TDP1 | |
| SCHEMBL1172293 | 0.79 | MEN1 (0.54) | HSD11B1HPGDALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9744436 | 0.79 | MEN1 (0.54) | HSD11B1HPGDALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115409-A2 | Indane derivatives, their production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1984-08-08 | — | — | EP | disclosed |