Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363713 | 0.81 | HTR6 (0.42) | LMNANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL7370397 | 0.80 | TSHR (0.52) | L3MBTL1POLBKDM4EGAAALDH1A1 | |
| SCHEMBL7366156 | 0.80 | SMN1; SMN2 (0.48) | POLBMAPTKMT2AGAAALDH1A1 | |
| SCHEMBL7363772 | 0.76 | CYP1A2 (0.47) | MAPTLMNAKMT2AGAAALDH1A1 | |
| SCHEMBL7398579 | 0.72 | POLB (0.48) | POLBMAPTKMT2APKMGAA | |
| SCHEMBL18221876 | 0.70 | PKM (0.59) | POLBLMNAKMT2APKMGAA | |
| SCHEMBL26620048 | 0.70 | TSHR (0.52) | L3MBTL1POLBMAPTLMNAALDH1A1 | |
| SCHEMBL14025597 | 0.69 | CXCR4 (0.54) | L3MBTL1POLBLMNAKDM4EKMT2A | |
| SCHEMBL14025697 | 0.69 | AKR1C3 (0.57) | POLBLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL29800475 | 0.68 | PKM (0.68) | POLBLMNAKMT2APKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200397-A1 | SULFONAMIDE SUBSTITUTED BENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICAMENTS | ELI LILLY AND COMPANY LIMITED (GB) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004087-A1 | SULFONAMIDE SUBSTITUTED BENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICAMENTS | ELI LILLY AND COMPANY LIMITED (GB) | 2001-01-18 | — | — | WO | disclosed |