Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370397 | 0.86 | TSHR (0.52) | POLBALDH1A1GAASMN1; SMN2USP2 | |
| SCHEMBL26620048 | 0.76 | TSHR (0.52) | POLBALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5772884 | 0.72 | ALDH1A1 (0.57) | POLBALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL7365554 | 0.72 | L3MBTL1 (0.47) | POLBALDH1A1GAAMAPTRAB9A | |
| SCHEMBL26620363 | 0.71 | TSHR (0.52) | POLBALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL24315792 | 0.71 | TSHR (0.57) | POLBALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL14025677 | 0.71 | DRD2 (0.58) | ALDH1A1MAPTTSHRDRD2MEN1 | |
| SCHEMBL7363713 | 0.70 | HTR6 (0.42) | ALDH1A1GAAMAPK1USP2CYP1A2 | |
| SCHEMBL26620047 | 0.70 | TSHR (0.50) | POLBALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL26620197 | 0.69 | TSHR (0.55) | POLBALDH1A1SMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200397-A1 | SULFONAMIDE SUBSTITUTED BENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICAMENTS | ELI LILLY AND COMPANY LIMITED (GB) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001004087-A1 | SULFONAMIDE SUBSTITUTED BENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICAMENTS | ELI LILLY AND COMPANY LIMITED (GB) | 2001-01-18 | — | — | WO | disclosed |