Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 15/20 | 0.78 |
| ▸ | MMP1 | P03956 | 14/20 | 0.78 |
| ▸ | MMP9 | P14780 | 14/20 | 0.78 |
| ▸ | MMP13 | P45452 | 14/20 | 0.78 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.78 |
| ▸ | MMP2 | P08253 | 1/20 | 0.78 |
| ▸ | MMP3 | P08254 | 1/20 | 0.78 |
| ▸ | MMP7 | P09237 | 1/20 | 0.78 |
| ▸ | MMP8 | P22894 | 1/20 | 0.78 |
| ▸ | MMP14 | P50281 | 1/20 | 0.78 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410572 | 0.90 | ALDH1A1 (0.90) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL7366360 | 0.89 | ADAM17 (0.81) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL7409543 | 0.88 | ADAM17 (1.00) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL7623960 | 0.81 | ADAM17 (0.76) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL6567121 | 0.81 | MMP1 (0.80) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL6565432 | 0.80 | CYP3A4 (0.84) | ADAM17MMP1MMP9MMP13ALDH1A1 | |
| SCHEMBL7953288 | 0.80 | MEN1 (0.75) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL14995881 | 0.79 | MMP9 (0.52) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL6567122 | 0.79 | MMP1 (1.00) | ADAM17MMP1MMP9MMP13ADAMTS4 | |
| SCHEMBL7405314 | 0.79 | SMN1; SMN2 (0.76) | ADAM17MMP1MMP9MMP13ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252143-A1 | METHOD FOR PREPARING ALPHA-SULFONYL HYDROXAMIC ACID DERIVATIVES | American Cyanamid Company (US) | 2002-10-30 | — | — | EP | disclosed |
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | WYETH HOLDINGS CORPORATION | 2002-07-25 | — | — | US | disclosed |
| WO-2001055112-A1 | METHOD FOR PREPARING ALPHA-SULFONYL HYDROXAMIC ACID DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099035-A1 | Method for preparing alpha-sulfonyl hydroxamic acid derivatives | MMP25, ADAMTS5, MMP9 | ADAM17 4/4885MMP1 14/4885MMP9 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.