Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CTSE | P14091 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954670 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCYP1A2CYP2D6MAPT | |
| SCHEMBL7362226 | 0.84 | ALDH1A1 (0.62) | SMN1; SMN2TSHRCYP1A2CYP2D6MAPT | |
| SCHEMBL4678395 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTRAB9AALDH1A1POLB | |
| SCHEMBL29611056 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTRAB9AALDH1A1POLB | |
| SCHEMBL42634 | 0.82 | CTSS (0.62) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL13583903 | 0.82 | CTSS (0.62) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL30968897 | 0.82 | CTSS (0.62) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL9582823 | 0.82 | CTSS (0.62) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL30992257 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTRAB9AALDH1A1POLB | |
| SCHEMBL7361383 | 0.81 | REN (0.63) | CTSSCTSKRENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |