Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | REN | P00797 | 5/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | CTSE | P14091 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361383 | 0.90 | REN (0.63) | RENCTSDCTSECTSSCTSK | |
| SCHEMBL7954670 | 0.87 | SMN1; SMN2 (0.50) | ALDH1A1CYP3A4RENCTSDCTSE | |
| SCHEMBL7366909 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1CYP3A4RENCTSDCTSE | |
| SCHEMBL29611056 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4678395 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7412552 | 0.82 | REN (0.60) | ALDH1A1CYP3A4RENCTSDCTSE | |
| SCHEMBL4750042 | 0.82 | CTSS (0.61) | CTSSCTSKBACE1 | |
| SCHEMBL30992257 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7329532 | 0.80 | BACE1 (0.62) | CTSSCTSKBACE1CA2 | |
| SCHEMBL9130009 | 0.79 | CA2 (0.59) | ALDH1A1RENCTSDCTSESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578745-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-01-19 | — | — | EP | disclosed |
| WO-1992017490-A1 | PHOSPHORUS CONTAINING COMPOUNDS AS INHIBITORS OF RETROVIRUSES | THE UPJOHN COMPANY (US) | 1992-10-15 | — | — | WO | disclosed |