Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 13/20 | 0.53 |
| ▸ | MMP2 | P08253 | 13/20 | 0.53 |
| ▸ | MMP3 | P08254 | 13/20 | 0.53 |
| ▸ | MMP13 | P45452 | 4/20 | 0.52 |
| ▸ | PDE4A | P27815 | 6/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6414410 | 0.82 | MMP1 (0.58) | MEP1BMMP1MMP2MMP3MMP13 | |
| SCHEMBL6415300 | 0.82 | MMP1 (0.68) | MEP1BMMP1MMP2MMP3MMP13 | |
| SCHEMBL8412098 | 0.81 | MMP1 (0.69) | MEP1BMMP1MMP2MMP3MMP13 | |
| SCHEMBL8121331 | 0.79 | MEP1B (0.54) | MEP1BMMP1MMP2MMP3MMP13 | |
| SCHEMBL7366924 | 0.77 | MMP2 (0.54) | MEP1BMMP1MMP2MMP3MMP13 | |
| SCHEMBL7410575 | 0.76 | MEP1B (0.91) | MEP1BMMP1MMP2MMP3MMP13 | |
| SCHEMBL7415077 | 0.72 | MMP9 (0.53) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL6934594 | 0.71 | MMP1 (0.73) | MMP1MMP2MMP3MMP13PDE4A | |
| SCHEMBL598146 | 0.69 | MMP3 (0.79) | MEP1BMMP1MMP2MMP3MMP13 | |
| SCHEMBL6928607 | 0.69 | MMP1 (1.00) | MMP1MMP2MMP3MMP13PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028716-A1 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1998025597-A2 | METHOD FOR TREATING AND PREVENTING HEART FAILURE AND VENTRICULAR DILATATION | WARNER-LAMBERT COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |