Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TGM1 | P22735 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23388381 | 0.98 | CCR6 (0.49) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL11974131 | 0.91 | CCR6 (0.55) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL7367495 | 0.87 | ALDH1A1 (0.58) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL24797627 | 0.87 | PRSS1 (0.45) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL10827358 | 0.85 | LMNA (0.60) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL30781926 | 0.85 | ATM (0.46) | ACHEL3MBTL1KMT2A | |
| SCHEMBL7367661 | 0.85 | CCR6 (0.51) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL164180 | 0.84 | ALDH1A1 (0.51) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL1678201 | 0.84 | DRD2 (0.50) | CCR6PAX8ALDH1A1F13A1TGM2 | |
| SCHEMBL31305080 | 0.84 | CCR6 (0.49) | CCR6PAX8ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606524-B2 | Synthesis of pyrrole acid derivatives | Infex Therapeutics Limited (GB) | 2026-04-21 | — | — | US | disclosed |
| WO-2024238872-A2 | ISOINDOLINONE-GLUTARIMIDE ANTIBODY CONJUGATES, AND USES THEREOF | FIREFLY BIO, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| US-20230286915-A1 | SYNTHESIS OF PYRROLE ACID DERIVATIVES | Infex Therapeutics Limited (GB) | 2023-09-14 | — | — | US | disclosed |
| US-20230286915-A1 | SYNTHESIS OF PYRROLE ACID DERIVATIVES | Infex Therapeutics Limited (GB) | 2023-09-14 | — | — | US | disclosed |
| EP-4225734-A1 | SYNTHESIS OF PYRROLE ACID DERIVATIVES | Infex Therapeutics Limited (GB) | 2023-08-16 | — | — | EP | disclosed |
| CN-116249533-A | Intestinal tract cracking type co-drug and preparation and application thereof | 轶诺(浙江)药业有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116209652-A | Synthesis of pyrrole acid derivatives | 英菲克斯治疗有限公司 | 2023-06-02 | — | — | CN | disclosed |
| WO-2022074385-A1 | SYNTHESIS OF PYRROLE ACID DERIVATIVES | Infex Therapeutics Limited (GB) | 2022-04-14 | — | — | WO | disclosed |
| US-20170058031-A1 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | SQUIBB & SONS LLC (US) | 2017-03-02 | — | — | US | disclosed |
| US-9499632-B2 | Human antibodies that bind CD22 and uses thereof | E.R. SQUIBB & SONS, L.L.C. (US) | 2016-11-22 | — | — | US | disclosed |
| WO-2008083312-A2 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF | MEDAREX, INC. (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2007038658-A2 | ANTIBODY-DRUG CONJUGATES AND METHODS OF USE | MEDAREX, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| EP-0688314-B1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-5804559-A | WATER SOLUBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-08 | — | — | US | disclosed |
| EP-0688314-A1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994021604-A1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-29 | — | — | WO | disclosed |
| US-5348953-A | Elastase inhibitor | MERCK & CO., INC. (US) | 1994-09-20 | — | — | US | disclosed |
| WO-1994013636-A1 | NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |
| EP-0525973-A2 | Substituted azetidinones as anti-inflammatory and antidegenerative agents | MERCK & CO. INC. (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1993000332-A1 | SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | MERCK & CO., INC. (US) | 1993-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12606524-B2 | Synthesis of pyrrole acid derivatives | SRR, ME1, CD79B | CCR6 797/4885PAX8 2843/4885ALDH1A1 743/4885 |
| US-20170058031-A1 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | CD2BP2, CD22, CD2 | CCR6 227/4885PAX8 2226/4885ALDH1A1 1167/4885 |
| US-20230286915-A1 | SYNTHESIS OF PYRROLE ACID DERIVATIVES | PEPD, ALDH18A1, PREP | CCR6 3584/4885PAX8 3146/4885ALDH1A1 872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.