Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.41 |
| ▸ | CTSS | P25774 | 7/20 | 0.41 |
| ▸ | CTSL | P07711 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321491 | 0.88 | PPARA (0.43) | CTSKCTSSCTSL | |
| SCHEMBL7369995 | 0.86 | CTSK (0.40) | CTSKCTSSCTSLPSMB1 | |
| SCHEMBL10522492 | 0.79 | KLK5 (0.46) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7314797 | 0.75 | MAPT (0.41) | CTSKCTSSCTSL | |
| SCHEMBL7408571 | 0.74 | MAPT (0.45) | — | |
| SCHEMBL7362345 | 0.72 | FPR2 (0.48) | CTSS | |
| SCHEMBL8876703 | 0.72 | FPR2 (0.48) | CTSS | |
| SCHEMBL9641169 | 0.69 | CTSS (0.41) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7316845 | 0.69 | CTSS (0.41) | CTSKCTSSCTSLCTSB | |
| SCHEMBL10242213 | 0.68 | ATM (0.46) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4885292-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-12-05 | — | — | US | disclosed |
| EP-0231919-A2 | N-Heterocyclic alcohol renin inhibitors | E.R. Squibb & Sons, Inc. (US) | 1987-08-12 | — | — | EP | disclosed |