SCHEMBL73700

SCHEMBL73700

O=C(O)C(Cc1ccccc1)NC(F)(F)P(=O)(O)O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACE P12821 3/20 0.51
NPSR1 Q6W5P4 1/20 0.50
FPR2 P25090 2/20 0.49
ECE1 P42892 1/20 0.49
PTPN1 P18031 3/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MME P08473 2/20 0.48
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.46
CPA1 P15085 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL739018 1.00 ACE (0.51) ACENPSR1FPR2ECE1PTPN1
SCHEMBL8703498 0.88 ACE (0.52) ACENPSR1FPR2ECE1PTPN1
SCHEMBL6254380 0.88 PTPN1 (0.56) ACEPTPN1
SCHEMBL71782 0.83 ACE (0.56) ACENPSR1FPR2ECE1L3MBTL1
SCHEMBL71781 0.83 ACE (0.56) ACENPSR1FPR2ECE1L3MBTL1
SCHEMBL933401 0.83 ACE (0.56) ACENPSR1FPR2ECE1L3MBTL1
SCHEMBL7322706 0.81 MME (0.59) ACEMMEACE2CPA1
SCHEMBL7348036 0.81 MME (0.59) ACEMMEACE2CPA1
SCHEMBL9223334 0.80 NPSR1 (0.55) ACENPSR1L3MBTL1MMEALDH1A1
SCHEMBL2622217 0.80 NPSR1 (0.55) ACENPSR1L3MBTL1MMEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192765-A1 PEPTIDES TARGETING SHP2 AND USES THEREOF Università Degli Studi di Roma "Tor Vergata" (IT) 2023-06-22 US claimed
EP-4114849-A1 PEPTIDES TARGETING SHP2 AND USES THEREOF Universita' degli Studi di Roma " Tor Vergata" (IT) 2023-01-11 EP claimed
WO-2021176072-A1 PEPTIDES TARGETING SHP2 AND USES THEREOF Università Degli Studi di Roma "Tor Vergata" (IT) 2021-09-10 WO claimed
US-20060148715-A1 Structural requirements for STAT3 binding and recruitment to phosphotyrosine ligands BAYLOR COLLEGE OF MEDICINE (US) 2006-07-06 US claimed
WO-2006069001-A2 STRUCTURAL REQUIREMENTS FOR STAT3 BINDING AND RECRUITMENT TO PHOSPHOTOTYROSINE LIGANDS BAYLOR COLLEGE OF MEDICINE (US) 2006-06-29 WO claimed
US-5801149-A PEPTIDS FOR INHIBITION OF PROTEINS JOSLIN D-ABETES CENTER, INC. (US) 1998-09-01 US claimed
WO-1994008600-A1 INHIBITION OF SIGNAL TRANSDUCTION MOLECULES JOSLIN DIABETES CENTER (US) 1994-04-28 WO claimed
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-28 US disclosed
US-20260115301-A1 INTRACELLULAR DELIVERY OF NUCLEIC ACIDS OHIO STATE INNOVATION FOUNDATION (US) 2026-04-30 US disclosed
EP-4717776-A2 POLYPEPTIDE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS Ohio State Innovation Foundation (US) 2026-04-01 EP disclosed
EP-4706689-A2 COMPOSITIONS FOR DELIVERY OF ANTISENSE COMPOUNDS Entrada Therapeutics, Inc. (US) 2026-03-11 EP disclosed
US-20260028630-A1 HYBRID OLIGONUCLEOTIDES ENTRADA THERAPEUTICS INC (US) 2026-01-29 US disclosed
US-12496350-B2 Cyclic peptidyl inhibitors of CAL-PDZ binding domain OHIO STATE INNOVATION FOUNDATION (US) 2025-12-16 US disclosed
WO-1996030332-A1 O-MALONYLTYROSYL COMPOUNDS, O-MALONYLTYROSYL COMPOUND-CONTAINING PEPTIDES, AND USES THEREOF THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTHA ND HUMAN SERVICES (US) 1996-10-03 WO disclosed
WO-1996026961-A2 PEPTIDYL COMPOUNDS COMPRISING AN ITIM MOTIF WHICH REGULATE HEMATOPOIETIC FUNCTION AND THEIR USE NATIONAL JEWISH CENTER FOR IMMUNOLOGY AND RESPIRATORY MEDICINE (US) 1996-09-06 WO disclosed
WO-1995034201-A1 pp60PIK: A DOWNSTREAM ELEMENT IN INSULIN SIGNALING JOSLIN DIABETES CENTER, INC. (US) 1995-12-21 WO disclosed
US-5475129-A Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-12-12 US disclosed
WO-1994008600-A1 INHIBITION OF SIGNAL TRANSDUCTION MOLECULES JOSLIN DIABETES CENTER (US) 1994-04-28 WO disclosed
WO-1993025561-A1 PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-12-23 WO disclosed
US-5264607-A Process of making benzylic α,α-diflurophosphonates from benzylic α-ketophosphorates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115301-A1 INTRACELLULAR DELIVERY OF NUCLEIC ACIDS SLC7A1, SRM, SLC6A19 ACE 4318/4885NPSR1 1435/4885FPR2 618/4885
US-20260028630-A1 HYBRID OLIGONUCLEOTIDES RNGTT, BCDIN3D, RNMT ACE 3520/4885NPSR1 2377/4885FPR2 2989/4885
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, SLC7A1, SLC6A15 ACE 1946/4885NPSR1 3759/4885FPR2 570/4885
US-20060148715-A1 Structural requirements for STAT3 binding and recruitment to phosphotyrosine ligands STAT3, JAK2, STAT5B ACE 4033/4885NPSR1 2608/4885FPR2 3373/4885
US-12496350-B2 Cyclic peptidyl inhibitors of CAL-PDZ binding domain CNBP, CALU, CLSPN ACE 1416/4885NPSR1 1332/4885FPR2 912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.