SCHEMBL73702

SCHEMBL73702

O=C(O)[C@](F)(Cc1ccccc1)N(F)CP(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.44
PTPN1 P18031 8/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
PTPRC P08575 1/20 0.39
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
CES1 P23141 1/20 0.38
LAP3 P28838 3/20 0.36
ANPEP P15144 1/20 0.36
ACP3 P15309 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8703505 0.82 FDPS (0.47) FDPSPTPN1SMN1; SMN2HIF1APTPRC
SCHEMBL29510761 0.81 SMN1; SMN2 (0.46) SMN1; SMN2HIF1ACES1
SCHEMBL28369074 0.79 SMN1; SMN2 (0.50) FDPSPTPN1SMN1; SMN2HIF1APTPRC
SCHEMBL7316714 0.79 SMN1; SMN2 (0.50) FDPSPTPN1SMN1; SMN2HIF1APTPRC
SCHEMBL6248908 0.75 PTPN1 (0.43) FDPSPTPN1SMN1; SMN2HIF1APTPRC
SCHEMBL30887346 0.75 SMN1; SMN2 (0.50) FDPSPTPN1SMN1; SMN2HIF1ACES1
SCHEMBL3736878 0.75 SMN1; SMN2 (0.50) FDPSPTPN1SMN1; SMN2HIF1ACES1
SCHEMBL29112713 0.75 SMN1; SMN2 (0.50) FDPSPTPN1SMN1; SMN2HIF1ACES1
SCHEMBL26127150 0.73 SMN1; SMN2 (0.44) FDPSPTPN1SMN1; SMN2HIF1ACES1
SCHEMBL8414267 0.69 PTPN1 (0.39) FDPSPTPN1PTPRCPGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060148715-A1 Structural requirements for STAT3 binding and recruitment to phosphotyrosine ligands BAYLOR COLLEGE OF MEDICINE (US) 2006-07-06 US claimed
WO-2006069001-A2 STRUCTURAL REQUIREMENTS FOR STAT3 BINDING AND RECRUITMENT TO PHOSPHOTOTYROSINE LIGANDS BAYLOR COLLEGE OF MEDICINE (US) 2006-06-29 WO claimed
US-5801149-A PEPTIDS FOR INHIBITION OF PROTEINS JOSLIN D-ABETES CENTER, INC. (US) 1998-09-01 US claimed
WO-1994008600-A1 INHIBITION OF SIGNAL TRANSDUCTION MOLECULES JOSLIN DIABETES CENTER (US) 1994-04-28 WO claimed
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-28 US disclosed
US-20260115301-A1 INTRACELLULAR DELIVERY OF NUCLEIC ACIDS OHIO STATE INNOVATION FOUNDATION (US) 2026-04-30 US disclosed
EP-4717776-A2 POLYPEPTIDE CONJUGATES FOR INTRACELLULAR DELIVERY OF NUCLEIC ACIDS Ohio State Innovation Foundation (US) 2026-04-01 EP disclosed
EP-4706689-A2 COMPOSITIONS FOR DELIVERY OF ANTISENSE COMPOUNDS Entrada Therapeutics, Inc. (US) 2026-03-11 EP disclosed
US-12496350-B2 Cyclic peptidyl inhibitors of CAL-PDZ binding domain OHIO STATE INNOVATION FOUNDATION (US) 2025-12-16 US disclosed
US-12454552-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2025-10-28 US disclosed
US-20250324980-A1 COMPOSITIONS FOR DELIVERY OF AGENTS INTO PLANT CELLS OHIO STATE INNOVATION FOUNDATION (US) 2025-10-23 US disclosed
US-20250270258-A1 BICYCLIC PEPTIDYL INHIBITORS OHIO STATE INNOVATION FOUNDATION 2025-08-28 US disclosed
US-5650293-A PROTEIN THAT MEDIATES INSULIN REGULATION OF 3'-PHOSPHATIDYL INOSITOL KINASE WITH NUCLEIC ACID SEQUENCES JOSLIN DIABETES CENTER, INC. (US) 1997-07-22 US disclosed
WO-1997008300-A9 CRYSTALLINE ZAP FAMILY PROTEINS 1997-05-22 WO disclosed
EP-0768821-A1 pp60PIK : A DOWNSTREAM ELEMENT IN INSULIN SIGNALING THE JOSLIN DIABETES CENTER, INC. (US) 1997-04-23 EP disclosed
WO-1995034201-A1 pp60PIK: A DOWNSTREAM ELEMENT IN INSULIN SIGNALING JOSLIN DIABETES CENTER, INC. (US) 1995-12-21 WO disclosed
US-5475129-A Phosphonoalkyl phenylalanine compounds suitably protected for use in peptide synthesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1995-12-12 US disclosed
WO-1994008600-A1 INHIBITION OF SIGNAL TRANSDUCTION MOLECULES JOSLIN DIABETES CENTER (US) 1994-04-28 WO disclosed
WO-1993025561-A1 PHOSPHONOALKYL PHENYLALANINE COMPOUNDS SUITABLY PROTECTED FOR USE IN PEPTIDE SYNTHESIS THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-12-23 WO disclosed
US-5264607-A Process of making benzylic α,α-diflurophosphonates from benzylic α-ketophosphorates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115301-A1 INTRACELLULAR DELIVERY OF NUCLEIC ACIDS SLC7A1, SRM, SLC6A19 FDPS 4277/4885PTPN1 4249/4885SMN1; SMN2 231/4885
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, SLC7A1, SLC6A15 FDPS 4608/4885PTPN1 4155/4885SMN1; SMN2 1836/4885
US-20250324980-A1 COMPOSITIONS FOR DELIVERY OF AGENTS INTO PLANT CELLS ARGLU1, PHAX, VMA21 FDPS 2954/4885PTPN1 4632/4885SMN1; SMN2 4524/4885
US-12454552-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof CHN2, TAP2, VIP FDPS 3735/4885PTPN1 4477/4885SMN1; SMN2 2867/4885
US-20060148715-A1 Structural requirements for STAT3 binding and recruitment to phosphotyrosine ligands STAT3, JAK2, STAT5B FDPS 3470/4885PTPN1 60/4885SMN1; SMN2 4364/4885
US-20250270258-A1 BICYCLIC PEPTIDYL INHIBITORS NFKBIA, IKBKG, NFRKB FDPS 2620/4885PTPN1 4339/4885SMN1; SMN2 4522/4885
US-12496350-B2 Cyclic peptidyl inhibitors of CAL-PDZ binding domain CNBP, CALU, CLSPN FDPS 2927/4885PTPN1 666/4885SMN1; SMN2 3588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.