Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883866 | 0.74 | TP53 (0.43) | ATMMAPTSMN1; SMN2PTBP1NPSR1 | |
| SCHEMBL7275212 | 0.74 | SIGMAR1 (0.45) | ATMMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL8827906 | 0.73 | ALDH1A1 (0.39) | ATMMAPTSMN1; SMN2PTBP1NPSR1 | |
| SCHEMBL7267935 | 0.71 | LMNA (0.44) | ATMMAPTSMN1; SMN2NPSR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL4885075 | 0.71 | ADRA1A (0.52) | MAPTSMN1; SMN2SLC6A2SLC6A3ADRA1A | |
| Hydrochloric Acid SCHEMBL4883921 | 0.71 | LMNA (0.45) | ATMMAPTSMN1; SMN2NPSR1SLC6A2 | |
| SCHEMBL6645288 | 0.71 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2ALDH1A1TDP1MEN1 | |
| SCHEMBL9102109 | 0.70 | TP53 (0.47) | ATMMAPTSMN1; SMN2PTBP1NPSR1 | |
| SCHEMBL7326485 | 0.70 | CACNA1B (0.45) | MAPTSMN1; SMN2ALDH1A1ADORA3MEN1 | |
| SCHEMBL9249991 | 0.70 | CACNA1B (0.45) | MAPTSMN1; SMN2ALDH1A1ADORA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |