Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.43 |
| ▸ | STS | P08842 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376664 | 0.88 | CYP1A2 (0.45) | GPBAR1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7373607 | 0.85 | HSD17B1 (0.44) | GPBAR1HSD17B1HSD17B2TSHRSMN1; SMN2 | |
| SCHEMBL7370356 | 0.82 | ALDH1A1 (0.48) | HSD17B2TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7371851 | 0.81 | CYP1A2 (0.43) | HSD17B1HSD17B2TSHRMEN1KMT2A | |
| SCHEMBL7371278 | 0.80 | ALDH1A1 (0.44) | GPBAR1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7368763 | 0.80 | RAB9A (0.43) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7968869 | 0.79 | KMT2A (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL358787 | 0.78 | ALDH1A1 (0.50) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7425044 | 0.78 | DRD2 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7422014 | 0.77 | SMN1; SMN2 (0.47) | TSHRSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0757670-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |