Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | KAT7 | O95251 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379409 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7379738 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7396002 | 0.71 | CKS1B (0.49) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL6635646 | 0.67 | PPARG (0.43) | SMN1; SMN2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL7448981 | 0.65 | ALDH1A1 (0.43) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7398244 | 0.65 | KEAP1 (0.42) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL4513023 | 0.62 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL8554556 | 0.61 | NPY1R (0.51) | — | |
| SCHEMBL7690658 | 0.60 | RAB9A (0.56) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT | |
| SCHEMBL7395648 | 0.60 | LMNA (0.60) | SMN1; SMN2MEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100795-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM ZENTRALE GMBH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000008014-A1 | DISUBSTITUTED BICYCLIC HETEROCYCLES HAVING, IN PARTICULAR, A THROMBIN INHIBITIVE EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-02-17 | — | — | WO | disclosed |