SCHEMBL7394302

SCHEMBL7394302

OB(O)c1ccccc1-c1ccccc1C(F)(F)F

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.46
CYP3A4 P08684 5/20 0.41
ALDH1A1 P00352 3/20 0.41
CYP2C19 P33261 3/20 0.41
CYP2D6 P10635 2/20 0.41
ALOX15 P16050 2/20 0.41
MAPK1 P28482 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
TRPA1 O75762 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
TRPV1 Q8NER1 1/20 0.40
NOTUM Q6P988 1/20 0.40
CYP1A2 P05177 4/20 0.39
ACP1 P24666 1/20 0.39
PDK2 Q15119 1/20 0.39
TSHR P16473 1/20 0.38
HIF1A Q16665 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22771448 0.85 MPL (0.46) HSD11B1CYP3A4ALDH1A1CYP2C19ALOX15
SCHEMBL29410834 0.83 ENPP2 (0.41) HSD11B1ALDH1A1TDP1
SCHEMBL4288 0.83 ENPP2 (0.41) HSD11B1ALDH1A1TDP1
SCHEMBL26374951 0.83 GPR3 (0.42) HSD11B1CYP3A4CYP2D6AKR1C3AKR1C2
SCHEMBL910658 0.80 ENPP2 (0.50)
SCHEMBL197671 0.80 HSD11B1 (0.56) HSD11B1CYP3A4ALDH1A1CYP2C19CYP2D6
SCHEMBL2557148 0.78 PDK2 (0.42) HSD11B1CYP3A4ALDH1A1CYP2C19CYP2D6
Hydrochloric Acid SCHEMBL29010139 0.78 HSD11B1 (0.54) HSD11B1CYP3A4ALDH1A1CYP2C19CYP2D6
SCHEMBL8022901 0.78 HSD11B1 (0.54) HSD11B1CYP3A4ALDH1A1CYP2C19CYP2D6
SCHEMBL2408381 0.74 TRPV6 (0.42) ALDH1A1PDK2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-09-28 US disclosed
CN-115380099-A Organic light emitting compound and organic light emitting device including the same 株式会社P&H TECH 2022-11-22 CN disclosed
US-5981754-A TREATMENT OF ANOXIA, ALZHEIMER'S DISEASE, SENILE DEMENTIA, SUBCORTICAL DEMENTIA SUCH AS HUNTINGTON'S CHOREA AND PARKINSON'S DISEASE, DEMENTIA CAUSED BY AIDS, NEUROPATHY SANOFI (FR) 1999-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230309388-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE OCIAD1, OCIAD2, SLCO4C1 HSD11B1 608/4885CYP3A4 318/4885ALDH1A1 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.