Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818420 | 0.85 | MAPT (0.53) | RAB9AL3MBTL1MAPTGAAALDH1A1 | |
| SCHEMBL10062555 | 0.78 | ALDH1A1 (0.47) | MAPTALOX15ALDH1A1TSHRHSD17B10 | |
| SCHEMBL14967622 | 0.74 | L3MBTL1 (0.44) | MTNR1AMTNR1BRAB9AL3MBTL1MAPT | |
| SCHEMBL11271674 | 0.73 | POLB (0.43) | MAPTALDH1A1MEN1KMT2AADRA1A | |
| SCHEMBL11297133 | 0.73 | MTNR1A (0.51) | MTNR1AMTNR1BRAB9AMAPTGAA | |
| SCHEMBL667989 | 0.71 | KCNA3 (0.41) | MTNR1AMTNR1BALOX15ALDH1A1HTR1A | |
| SCHEMBL11013902 | 0.71 | ALDH1A1 (0.42) | MTNR1AMTNR1BALOX15ALDH1A1NPC1 | |
| SCHEMBL19091769 | 0.71 | KCNA3 (0.41) | MTNR1AMTNR1BALOX15ALDH1A1HTR1A | |
| SCHEMBL11292129 | 0.71 | LMNA (0.64) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7269669 | 0.70 | KCNA3 (0.44) | ALOX15ALDH1A1HTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002006215-A1 | 3-ARYLSULFONYL-2-HYDROXY-2-METHYLPROPANOIC ACID DERIVATES | PHARMACIA ITALIA S.P.A. (IT) | 2002-01-24 | — | — | WO | disclosed |