Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.47 |
| ▸ | MMP9 | P14780 | 9/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | CFB | P00751 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401476 | 0.74 | HSD17B10 (0.45) | PIN1NPY5RGRIN1GRIN2BALDH1A1 | |
| SCHEMBL7400871 | 0.67 | TPH1 (0.43) | GRIN1GRIN2BALDH1A1PDE10A | |
| SCHEMBL14287936 | 0.65 | SCN10A (0.56) | PIN1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL9314968 | 0.65 | IDO1 (0.53) | ALDH1A1POLB | |
| SCHEMBL7406972 | 0.65 | F2 (0.45) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL7080833 | 0.65 | ALDH1A1 (0.58) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL20305429 | 0.64 | PIN1 (1.00) | PIN1CSNK1A1CSNK1DGSK3BCSNK1G2 | |
| SCHEMBL876560 | 0.64 | SMN1; SMN2 (0.53) | MMP2MMP9ALDH1A1 | |
| SCHEMBL7433448 | 0.64 | ALDH1A1 (0.56) | PIN1ALDH1A1POLB | |
| SCHEMBL4069591 | 0.64 | PIN1 (0.63) | PIN1CSNK1A1CSNK1DGSK3BCSNK1G2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |