Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378278 | 0.78 | HSD17B10 (0.63) | HSD17B10ALDH1A1GRIN1GRIN2BPIN1 | |
| SCHEMBL7401472 | 0.74 | MMP2 (0.47) | ALDH1A1GRIN1GRIN2BPDE10APIN1 | |
| SCHEMBL4069591 | 0.73 | PIN1 (0.63) | ALDH1A1GRIN1GRIN2BPIN1APEX1 | |
| SCHEMBL7400871 | 0.70 | TPH1 (0.43) | HSD17B10ALDH1A1GRIN1GRIN2BPDE10A | |
| SCHEMBL3378268 | 0.69 | HSD17B10 (0.63) | HSD17B10ALDH1A1GRIN1GRIN2BPIN1 | |
| SCHEMBL3922051 | 0.68 | HPGD (0.70) | HSD17B10ALDH1A1POLBAPEX1TDP1 | |
| SCHEMBL7068290 | 0.67 | HSD17B10 (0.60) | HSD17B10ALDH1A1PKMPOLBSMN1; SMN2 | |
| SCHEMBL7653726 | 0.67 | TDP1 (0.59) | ALDH1A1GRIN1GRIN2BPIN1POLB | |
| SCHEMBL3391734 | 0.67 | GRIN1 (0.55) | ALDH1A1GRIN1GRIN2BPIN1POLB | |
| SCHEMBL7366450 | 0.66 | RAB9A (0.64) | ALDH1A1PKMGRIN1GRIN2BPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |