Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 4/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10981257 | 0.97 | CA3 (0.44) | CA3CA14ALOX15CA12CA2 | |
| Hydrochloric Acid SCHEMBL10878287 | 0.97 | CA3 (0.44) | CA3CA14ALOX15CA12CA2 | |
| Hydrochloric Acid SCHEMBL11113929 | 0.97 | CA3 (0.44) | CA3CA14ALOX15CA12CA2 | |
| SCHEMBL970836 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL10984148 | 0.95 | CA3 (0.42) | CA3CA14ALOX15CA12CA2 | |
| Hydrochloric Acid SCHEMBL11113931 | 0.92 | CA3 (0.44) | CA3CA14ALOX15CA12CA2 | |
| SCHEMBL694368 | 0.87 | CA3 (0.40) | CA3CA14ALOX15CA12CA2 | |
| Hydrochloric Acid SCHEMBL10895645 | 0.86 | DNM1 (0.41) | CA3CA14ALOX15CA12CA2 | |
| Sulfuric Acid SCHEMBL11345321 | 0.85 | LMNA (0.46) | CA3CA14ALOX15CA12CA2 | |
| Hydrochloric Acid SCHEMBL11205797 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173401-A1 | PROCESS FOR THE SYNTHESIS OF ARYLDIAZONIUM SALTS USING NITROGEN OXIDES IN OXYGEN-CONTAINING GAS STREAMS, ESPECIALLY FROM INDUSTRIAL WASTE GASES | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-8784980-B2 | Film prepared from a casting composition comprising a polymer and surface modified hexagonal boron nitride particles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-22 | — | — | US | disclosed |
| CN-102421701-B | Surface modified hexagonal boron nitride particles | DU PONT | 2014-07-16 | — | — | CN | disclosed |
| CN-102421829-B | A film prepared from a casting composition comprising a polymer and surface modified hexagonal boron nitride particles | DU PONT | 2014-05-07 | — | — | CN | disclosed |
| CN-102421841-B | Composite of polymer and surface modified hexagonal boron nitride particles | DU PONT | 2014-04-09 | — | — | CN | disclosed |
| US-8440292-B2 | Multi-layer article for flexible printed circuits | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-14 | — | — | US | disclosed |
| US-8288466-B2 | Composite of a polymer and surface modified hexagonal boron nitride particles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-16 | — | — | US | disclosed |
| US-8258346-B2 | Surface modified hexagonal boron nitride particles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-09-04 | — | — | US | disclosed |
| CN-102421841-A | Composite of polymer and surface modified hexagonal boron nitride particles | DU PONT | 2012-04-18 | — | — | CN | disclosed |
| CN-102421701-A | Surface modified hexagonal boron nitride particles | DU PONT | 2012-04-18 | — | — | CN | disclosed |
| EP-2429815-A2 | MULTI-LAYER ARTICLE FOR FLEXIBLE PRINTED CIRCUITS | E. I. du Pont de Nemours and Company (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-2429943-A2 | SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | E. I. du Pont de Nemours and Company (US) | 2012-03-21 | — | — | EP | disclosed |
| US-20100288968-A1 | COMPOSITE OF A POLYMER AND SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2010-11-18 | — | — | US | disclosed |
| WO-2010132512-A2 | SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | WO | disclosed |
| US-20100291365-A1 | FILM PREPARED FROM A CASTING COMPOSITION COMPRISING A POLYMER AND SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292508-A1 | SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | E. I. DU POND DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100291371-A1 | MULTI-LAYER ARTICLE FOR FLEXIBLE PRINTED CIRCUITS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010132510-A2 | COMPOSITE OF A POLYMER AND SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132519-A2 | A FILM PREPARED FROM A CASTING COMPOSITION COMPRISING A POLYMER AND SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | WO | disclosed |
| WO-2010132522-A2 | MULTI-LAYER ARTICLE FOR FLEXIBLE PRINTED CIRCUITS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292508-A1 | SURFACE MODIFIED HEXAGONAL BORON NITRIDE PARTICLES | SHROOM3, HAO2, NOXO1 | ACHE 4775/4885CA3 1003/4885CA14 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.