Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607306 | 0.84 | SLC15A1 (0.47) | CTRB1CTSLSLC15A1LTA4H | |
| SCHEMBL2367781 | 0.81 | IDO1 (0.44) | SLC15A1LTA4HLAP3 | |
| SCHEMBL2367196 | 0.78 | CTSC (0.45) | CTRB1CTSLSLC15A1ACEMME | |
| Trifluoroacetic Acid SCHEMBL28278079 | 0.76 | ALPI (0.54) | CTRB1SLC15A1LTA4HLAP3 | |
| SCHEMBL2367378 | 0.74 | PSMB1 (0.41) | CTSLLTA4HMMEECE1 | |
| SCHEMBL2367512 | 0.73 | CTSL (0.41) | CTSLMME | |
| SCHEMBL27873595 | 0.72 | LTA4H (0.54) | SLC15A1LTA4HLAP3 | |
| SCHEMBL304415 | 0.72 | LTA4H (0.54) | SLC15A1LTA4HLAP3 | |
| SCHEMBL169622 | 0.72 | LTA4H (0.54) | SLC15A1LTA4HLAP3 | |
| SCHEMBL2367341 | 0.72 | ACE (0.45) | CTSLACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937042-A1 | HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998017643-A1 | HETEROARYL SUCCINAMIDES AND THEIR USE AS METALLOPROTEINASE INHIBITORS | AGOURON PHARMACEUTICALS, INC. (US) | 1998-04-30 | — | — | WO | disclosed |