Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417922 | 0.80 | RPS6KB1 (0.43) | SLC6A3SLC6A4SLC6A2HTR2ARPS6KB1 | |
| Hydrochloric Acid SCHEMBL7408544 | 0.77 | RPS6KB1 (0.41) | SLC6A3SLC6A4SLC6A2HTR2ARPS6KB1 | |
| SCHEMBL7411614 | 0.77 | GAA (0.53) | — | |
| SCHEMBL7416706 | 0.76 | KMT2A (0.47) | HTR2A | |
| SCHEMBL7407232 | 0.76 | FAAH (0.51) | — | |
| SCHEMBL7412633 | 0.72 | CYP11B2 (0.42) | RPS6KB1 | |
| SCHEMBL7325604 | 0.71 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL21382026 | 0.71 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL21382056 | 0.71 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL30149800 | 0.71 | OPRD1 (0.53) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |