Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407232 | 0.89 | FAAH (0.51) | KMT2AMEN1 | |
| SCHEMBL7409826 | 0.84 | ALDH1A1 (0.46) | KMT2AHTR2AALDH1A1TSHRMEN1 | |
| SCHEMBL7409872 | 0.78 | HTR2A (0.43) | HTR2AOPRM1TMEM97ALDH1A1TSHR | |
| SCHEMBL7411614 | 0.78 | GAA (0.53) | KMT2AALDH1A1MEN1 | |
| SCHEMBL7411261 | 0.78 | SLC6A3 (0.46) | KMT2ASMN1; SMN2 | |
| SCHEMBL7409332 | 0.76 | SLC6A3 (0.41) | HTR2A | |
| SCHEMBL7411767 | 0.75 | HTR2A (0.59) | HTR2ATSHR | |
| SCHEMBL7414540 | 0.73 | MEN1 (0.54) | KMT2AHTR2AOPRM1ALDH1A1MEN1 | |
| SCHEMBL7412596 | 0.72 | HTR2A (0.41) | HTR2AOPRM1TMEM97ALDH1A1TSHR | |
| SCHEMBL7413028 | 0.71 | OPRM1 (0.57) | HTR2AOPRM1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |