Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416706 | 0.89 | KMT2A (0.47) | KMT2AMEN1 | |
| SCHEMBL7415265 | 0.83 | GLA (0.54) | FAAHKMT2AMEN1GLANPC1 | |
| SCHEMBL7411614 | 0.77 | GAA (0.53) | KMT2AMEN1 | |
| SCHEMBL7409332 | 0.76 | SLC6A3 (0.41) | — | |
| SCHEMBL7409826 | 0.72 | ALDH1A1 (0.46) | KMT2AMEN1ALOX15 | |
| SCHEMBL7411767 | 0.72 | HTR2A (0.59) | — | |
| SCHEMBL7322620 | 0.71 | KDM4E (0.61) | FAAHKMT2AMEN1NPC1 | |
| SCHEMBL23848213 | 0.70 | CYP1A2 (0.54) | FAAHKMT2AGLANPC1 | |
| SCHEMBL8252174 | 0.70 | ALDH1A1 (0.63) | FAAHNPC1 | |
| SCHEMBL3600315 | 0.69 | FAAH (1.00) | FAAHKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |