Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703390 | 0.77 | MTNR1A (0.54) | LMNATP53HPGDNPSR1TRPM8 | |
| SCHEMBL7698345 | 0.76 | KMT2A (0.34) | SLC6A2SLC6A4NPC1EDNRA | |
| SCHEMBL7413568 | 0.75 | LTB4R (0.43) | LTB4RLTB4R2NPC1LMNATP53 | |
| Lithium Ion SCHEMBL7703568 | 0.68 | SLC6A9 (0.43) | LTB4RLTB4R2SLC6A2SLC6A4NPC1 | |
| SCHEMBL7704449 | 0.68 | SLC6A9 (0.65) | — | |
| SCHEMBL3421120 | 0.66 | ESR1 (0.44) | LTB4RLTB4R2CYP2D6LMNA | |
| SCHEMBL29960496 | 0.65 | ALDH1A1 (0.46) | LTB4RLTB4R2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL19450719 | 0.65 | CYP19A1 (0.44) | LTB4RLTB4R2NPC1LMNATP53 | |
| SCHEMBL19452860 | 0.65 | CYP19A1 (0.44) | LTB4RLTB4R2NPC1LMNATP53 | |
| SCHEMBL12187737 | 0.64 | KMT2A (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |
| EP-1100769-A1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | Akzo Nobel N.V. (NL) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007978-A1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL N.V. (NL) | 2000-02-17 | — | — | WO | disclosed |