Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704449 | 0.84 | SLC6A9 (0.65) | MTNR1AMTNR1BSLC6A9 | |
| SCHEMBL7413569 | 0.77 | LTB4R (0.41) | NPSR1TRPM8EDNRALMNATP53 | |
| SCHEMBL7698345 | 0.77 | KMT2A (0.34) | MTNR1AMTNR1BGAAEDNRA | |
| SCHEMBL7703389 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BSLC6A9SIGMAR1CYP11B2 | |
| SCHEMBL7704407 | 0.73 | SLC6A9 (0.60) | MTNR1AMTNR1BSLC6A9SIGMAR1 | |
| SCHEMBL9510931 | 0.72 | MTNR1A (0.63) | MTNR1AMTNR1BSLC6A9SIGMAR1PRCP | |
| SCHEMBL12591535 | 0.72 | SLC6A9 (0.71) | MTNR1AMTNR1BSLC6A9SIGMAR1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7706012 | 0.71 | MTNR1A (0.65) | MTNR1AMTNR1BSLC6A9SIGMAR1GAA | |
| Hydrochloric Acid SCHEMBL7706074 | 0.71 | SLC6A9 (0.70) | MTNR1AMTNR1BSLC6A9SIGMAR1CYP11B2 | |
| SCHEMBL1455049 | 0.70 | IDO1 (0.56) | IDO1RETHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |